Depigment
























The management of pigment spots and melasma is a major aesthetic concern for many patients. As a practitioner, you are looking for effective and safe solutions. Our selection of professional depigmenting products is designed to meet these needs, offering advanced formulations to target skin hyperpigmentation.
Understanding Hyperpigmentation and Professional Depigmenting Products
Hyperpigmentation manifests as an excessive production of melanin, leading to the appearance of dark spots on the skin. These spots can be of various natures: solar lentigines, post-inflammatory spots, or melasma, a hormonal hyperpigmentation often complex to treat. Depigmenting products act by inhibiting melanogenesis, promoting cell renewal, or dispersing existing pigments.
Different Forms of Hyperpigmentation
- Solar Lentigines (age spots): Caused by chronic sun exposure, they generally appear on exposed areas such as the face, hands, and décolleté.
- Post-Inflammatory Hyperpigmentation (PIH): Result of inflammation or skin trauma (acne, injuries, aesthetic procedures), more common in darker skin types.
- Melasma (chloasma): Characterized by symmetrical spots, often on the face, exacerbated by hormones (pregnancy, contraceptives) and sun exposure.
Key Depigmenting Active Ingredients
Depigmenting formulations integrate a synergy of active ingredients for targeted action:
- Kojic acid and azelaic acid: Inhibit tyrosinase, a key enzyme in melanin production.
- Vitamin C (ascorbic acid): Powerful antioxidant that reduces melanin production and brightens the complexion.
- Retinoids (retinol, tretinoin): Accelerate cell renewal and disperse melanin.
- Tranexamic acid: Acts on the inflammatory cascade and vascularization involved in melasma.
- Niacinamide (vitamin B3): Blocks the transfer of melanosomes to keratinocytes.
- Hydroquinone: Powerful tyrosinase inhibitor, often used under strict medical supervision.
Therapeutic Approaches for Pigment Spots and Melasma
Professional depigmenting products come in various forms to adapt to treatment protocols:
- Chemical peels: Acids such as glycolic, lactic, salicylic acid, or TCA are used to exfoliate the superficial layers of the skin and reduce pigmentation. Specific peels like Cosmelan or Dermamelan by Mesoestetic are recognized for their effectiveness on melasma.
- Topical solutions: Creams, serums, and masks concentrated in depigmenting active ingredients, to be applied in-office or at home as part of a protocol.
- Mesotherapy: Injections of depigmenting cocktails directly into the dermis for targeted action.
The Importance of Sun Protection
Whatever the chosen approach, sun protection is a fundamental pillar of any depigmenting treatment. UV exposure is a major triggering and aggravating factor for hyperpigmentation. Daily use of a broad-spectrum sunscreen (SPF 50+) is essential to prevent recurrence and protect treated skin.
Our range includes solutions from recognized brands like Mesoestetic, offering comprehensive protocols for the management of pigment spots and melasma, allowing practitioners to offer visible and lasting results to their patients.