Mesoestetic: Complete guide to the Cosmelan, Dermamelan, Mesopeel and c.prof ranges

Sourcing dermo-cosmetic solutions and aesthetic medical devices requires absolute rigor from healthcare professionals and clinic managers. Faced with a growing demand for targeted solutions for hyperpigmentation, skin aging, and skin preparation, the Mesoestetic Pharma Group laboratory has established itself as a global benchmark. This guide is exclusively intended for B2B buyers (doctors, surgeons, dermatologists, aesthetic clinics) wishing to structure their treatment offering with the Cosmelan, Dermamelan, Mesopeel, c.prof, Age Element, and Mesoprotech ranges. The objective is to detail the technical specifications, the characteristics of each reference, and the European regulatory framework, in order to facilitate inventory management and product selection within your healthcare facility.

Why integrate Mesoestetic solutions into your clinic

Founded in Barcelona, Mesoestetic Pharma Group stands out for its pharmaceutical approach to dermo-cosmetics and aesthetic medicine. The choice to integrate this brand into a clinic's portfolio is based on several technical and structural characteristics sought by professional buyers.

Firstly, the laboratory designs its ranges according to a logic of synergy. Professional treatments (performed in-clinic) are systematically coupled with homecare maintenance protocols. This continuity makes it possible to maintain the action of the active ingredients formulated by the manufacturer and to stabilize the announced results. Secondly, Mesoestetic invests heavily in research on epigenetics and the regulation of melanogenesis, thus offering highly concentrated and stable formulations. Finally, the laboratory operates under strict quality standards, including ISO 9001 and ISO 13485 certifications, guaranteeing practitioners traceability and pharmaceutical-grade safety for medical devices and professional cosmetics.

Cosmelan Treatment 1 pack

The Cosmelan pack is one of the laboratory's flagship references, globally recognized in the management of pigmentary disorders. It is a complete set designed to initiate the depigmentation process in the clinic and continue it at home.

Technology

The technology of the Cosmelan Treatment 1 pack relies on a dual action defined by the manufacturer: corrective and regulatory. The formulation aims to inhibit the action of tyrosinase, the key enzyme in the melanogenesis process. The complex of active ingredients acts on the different phases of melanin production to reduce the appearance of existing spots while limiting the formation of new hyperpigmentations.

Concentration & volume

This product is packaged as a pack (Volume: 1 complete pack). It generally contains the degreasing solution (for skin preparation), the Cosmelan 1 mask (for professional application in the clinic), the Cosmelan 2 cream (for home maintenance), as well as complementary care products such as Melan Recovery cream and Mesoprotech Melan 130+ sun protection. It does not contain lidocaine.

Brand specificities

Classified in the professional cosmetics category, the Cosmelan protocol is Mesoestetic's flagship method. The laboratory highlights its hydroquinone-free formulation, favoring a complex blend of acids (azelaic, kojic, phytic) and plant extracts to ensure a depigmenting action according to European cosmetic standards.

Dermamelan Treatment Cream 30g

The Dermamelan Treatment cream is the pillar of the home maintenance phase of the professional Dermamelan protocol, intended for more severe or resistant hyperpigmentations.

Technology

The Dermamelan Treatment Cream 30g uses active ingredient vectorization technology. According to the laboratory's data, this post-protocol depigmenting cream incorporates sustained-release systems (liposomes) that allow the ingredients to reach their cellular target optimally. The technical objective is to maintain the tyrosinase blockade initiated during the in-clinic treatment.

Concentration & volume

The product is presented in a 30g airless pump bottle. This technical packaging preserves the integrity of active ingredients sensitive to oxidation (notably acids and vitamins) throughout the product's period of use. It is formulated without lidocaine.

Brand specificities

Dermamelan is positioned above Cosmelan in terms of intensity of action according to the manufacturer's classification. Although it is a professional cosmetic, its distribution is strictly regulated and its use is exclusively part of the continuity of the professional Dermamelan mask applied by the practitioner.

Mesopeel MD Melanostop Tranex

The Mesopeel MD range represents the medical evolution of Mesoestetic's chemical peels, designed to meet the requirements of the new European medical device regulation.

Technology

The Mesopeel MD Melanostop Tranex is based on a combined chemical peel technology. Its formulation synergizes tranexamic acid with other exfoliating and depigmenting agents. Tranexamic acid is recognized in scientific literature for its action on the vascular component of hyperpigmentation and its interaction with plasminogen, thus offering a multidimensional approach according to the manufacturer's specifications.

Concentration & volume

This peel is packaged in an amber glass bottle with a volume of 50ml, guaranteeing the stability of the acid solution against light. It is a solution for strictly professional use, formulated without lidocaine.

Brand specificities

The "MD" (Medical Device) designation indicates that this product meets the strict criteria of European class medical devices. Mesoestetic thus guarantees a superior level of purity, controlled pH, and clinical safety, reserving this product for qualified doctors for performing controlled chemical exfoliations.

c.prof 210 Depigmentation Solution

Mesoestetic's c.prof line offers ready-to-use sterile active ingredient cocktails, intended for transdermal administration techniques.

Technology

The c.prof 210 Depigmentation Solution is an aesthetic (transdermal) mesotherapy solution. The laboratory has formulated this cocktail with antioxidant, brightening, and regulating agents (such as vitamin C, tranexamic acid, and idebenone). The technology relies on the immediate bioavailability of the active ingredients when introduced into the superficial layers of the epidermis via microneedling or electroporation devices.

Concentration & volume

The professional packaging comes in the form of a box containing 5 sterile vials of 5ml each (Total volume: 5×5ml). This single-dose format guarantees the sterility of the product during each session. The solution does not contain lidocaine.

Brand specificities

Unlike the x.prof range which offers isolated active ingredients, the c.prof range (active ingredient cocktail) offers ready-to-use synergistic formulas. Mesoestetic guarantees the sterility and apyrogenicity of these solutions, meeting the standards required for transcutaneous applications in a medical practice.

Age Element Firming Cream 50ml

Beyond pigmentation, Mesoestetic innovates in the management of skin aging with its Age Element range, based on the latest advances in epigenetics.

Technology

The Age Element Firming Cream 50ml incorporates the patented [meso]epigen system™ complex. According to the laboratory, this technology acts on epigenetic markers to reactivate cellular regeneration mechanisms. The firming cream is specifically formulated with peptides and phytoactives to target loss of elasticity and improve tissue turgor.

Concentration & volume

The product is packaged in a 50ml glass jar. Its texture is developed to offer a sensoriality adapted to mature skin, with an immediate tightening finish described by the manufacturer. It is a cosmetic without lidocaine.

Brand specificities

The Age Element range represents Mesoestetic's premium anti-aging segment. It is designed to prolong and optimize the results of tightening treatments performed in the clinic (such as anti-aging peels or radiofrequency), relying on a personalized approach to skin aging.

Mesoprotech Melan 130+

Sun protection is a non-negotiable component of any aesthetic protocol, especially when using peels or depigmenting treatments.

Technology

The Mesoprotech Melan 130+ uses Mesoprotech® complex technology. It offers very broad-spectrum protection against UVA, UVB, visible light (HEV), and infrared (IR) radiation. The manufacturer has specifically integrated a depigmenting active ingredient (azeloglycine) to regulate melanin synthesis during sun exposure.

Concentration & volume

This sun fluid is presented in a 50ml tube. Its formula, without lidocaine, is highly concentrated in high-tech sun filters to achieve a sun protection factor (SPF) greater than 130, according to the laboratory's in vitro tests.

Brand specificities

The specificity of this product lies in its tinted texture. The integrated pigments help avoid the "white cast" effect typical of very high sun protection, while unifying the complexion. It is the essential closing product recommended by Mesoestetic after any dermo-aesthetic procedure.

Comparative table of Mesoestetic solutions

To facilitate the management of your B2B purchases, here is a summary of the specifications of the products presented:

Regulatory framework and logistics

The acquisition and use of professional-use products and medical devices are subject to a strict European regulatory framework, particularly since the entry into force of the MDR regulation (Medical Device Regulation - EU 2017/745).

The products in the Mesopeel MD range, for example, benefit from a medical CE marking, certifying their compliance with safety and performance requirements for clinical use. The sterile solutions in the c.prof range also meet rigorous pharmaceutical manufacturing standards guaranteeing their apyrogenicity. For professional cosmetics (Cosmelan, Dermamelan, Age Element), Mesoestetic complies with the European cosmetics regulation (CE 1223/2009), ensuring registration on the CPNP portal and the creation of Product Information Files (PIF).

In terms of logistics, although the majority of Mesoestetic products can be stored at room temperature (unlike the strict cold chain required for certain toxins or specific fillers), maintaining a controlled storage environment (away from humidity, direct light, and extreme temperature variations) is imperative to preserve the integrity of sensitive active ingredients such as vitamin C or fruit acids.

How to order from Filler Distribution

Filler Distribution is your trusted B2B partner for sourcing Mesoestetic products. Our platform is designed to meet the requirements of healthcare professionals and aesthetic clinics.

When creating your professional account, verification of your RPPS number (or European equivalent) is required for access to medical devices for strictly professional use. We guarantee total traceability: each shipped batch is recorded, allowing rigorous tracking from the manufacturing laboratory to your practice. Furthermore, aware of the inventory management imperatives of clinics, we offer express delivery solutions (D+1) with secure packaging, ensuring that the products reach you in optimal conditions of integrity.

Frequently Asked Questions (FAQ)

What is the technical difference between the Cosmelan and Dermamelan ranges?

According to the Mesoestetic laboratory, the difference lies in the concentration of active ingredients and the level of action. Cosmelan is formulated for moderate hyperpigmentations, while Dermamelan incorporates more complex vectorization systems and is intended for more intense or resistant hyperpigmentations.

Do c.prof solutions require a medical CE marking?

The c.prof solutions are sterile products intended for transcutaneous application (topical, cosmetic microneedling). Their regulatory status depends on the claimed application method. They are manufactured under strict sterility standards but are not classified as injectable implants (which require a class III medical CE marking).

How to verify the authenticity of the ordered Mesoestetic products?

Filler Distribution sources through official channels. Authenticity is guaranteed by the traceability of the batch numbers appearing on each package, the manufacturer's security seal, and the presence of European legal notices on the packaging.

Does Mesoprotech Melan 130+ leave white residues on the skin?

No, the manufacturer has specifically formulated this product with light colored pigments. This technical design neutralizes the white cast inherent to very high protection physical filters, offering a natural and unifying finish for the skin.

Related products and resources

To deepen your knowledge and complete your therapeutic arsenal, explore our dedicated categories, products, and articles:

• Discover the entire Mesoestetic range
• Cosmelan Treatment 1 pack
• Dermamelan Treatment Cream 30g
• Mesopeel MD Melanostop Tranex
• c.prof 210 Depigmentation Solution
• Age Element Firming Cream 50ml
• Mesoprotech Melan 130+
• How to choose your hyaluronic acid filler
• Cold-chain: why it is crucial for fillers
• Top 5 premium fillers 2026 — clinical comparison

This article does not constitute medical advice. The medical devices described are reserved for qualified healthcare professionals (RPPS required). The choice of product, injection technique, and patient management are the exclusive responsibility of the practitioner.